Samuel William Christopher Watson is an American singer and rapper. Usually, he is well known by “Krizz Kaliko (stage name). He was born on 7th March, 1974 in Kansas City Missouri. In the end of 1990’s, Krizz Kaliko started his successful career in the field of music and earned a name in top musical list. Vitiligo, Genius, Son of Sam and Walk on Water are his famous musical albums.

Vitiligo also affected him. It can be observed in his songs of debut album, “vitiligo” which show compassion for vitiligo patients. He thinks that vitiligo patients, because of their strange look are sometimes disliked by their close ones.

He said that now in anticipation of vitiligo you may have thought that it is a fictitious disease.  It is also said by him that vitiligo is an invention of Michael Jackson which took place due to bleaching of his skin but this is just rumor…vitiligo is a disease which have existence.

Krizz’s debut album, “Vitiligo” was released on 6th May, 2008. The title “vitiligo” is given to this album because he discovered this disease in 2008. In this way anyone easily learns that he was stigmatized by his condition.


Thomas Lennon, an American well known actor, comedian, director and producer was born on August 9, 1970 in Chicago. In 1988, he graduatedfrom Oak Park River Forest High School and then he got admission in NYU (New York University). He is a citizen of Oak Park, Illinois, U.S.

His role as “Lieutenant Jim” in Comedy Central Series “Rano 911” got so popularity and brought him on top of the list. He is a good screenwriter and also has ability of writing books. “50 Greatest Comedy Sketches of All Time” have shown him as a great writer. He worked in many documentary films as a Director and also worked in many TV shows and channels.

As far as his personal life is concerned, he married with Jenny Robertson, a famous actress and lives with his son Olive in Los Angeles. Unfortunately, he became victim of Vitiligo. He experienced it on his face, hands and hips.


Amitabh Bachan… He who must not be named. He is a famous film actor, host, singer and producer. First, he gained popularity in 1970 as an “angry young man”. It was the beginning of his career. Now he is a prominent figure of Bollywood. Some people become the guiding star of their field just like Amitabh Bachan. He is an icon of Indian film industry. Amitabh possesses gorgeous personality. Commonly, people know him by his nick names such as Amit G, Muno bhai, Big B and Angry young man. His deep and baritone voice also make him unique.
Amitabh Bachan has won many awards in which three National Film Awards and thirteen Filmfare Awards are included. He won his first National Film Awards as a best newcomer. He also took part in politics in 1984-1987. In November 2005, He was ill with the infection of small intestine. So, he has to undergo surgery. At that time, his projects remained pending including television show “Kaun Bnega Crorepati.” A fact come into know about him that he has been suffering with vitiligo.


Michael Jackson was a renowned American singer, artist, philanthropist, dancer and business man. According to Guinness World Record, he is known as successful artiste of all ages. Michael Jackson is a king of pop music. His multitalented performances made him a global figure of America Africa culture.
He started his career in 1971 and moved heaven and Earth to earn fame. Nature blessed him a versatile personality including distinctive voice
and eye-popping dance. In 1993, he gave a statement that he is affected by vitiligo. Actually, his complexion was medium-brown which gradually whitened due to this disorder. There were brown spots on Michael’s body at his arms, nose and lips. He has to surgery his face to cover this problem. But rumor prevailed by media that he started bleaching his skin. His disorder is objected by saying that if he has vitiligo then why he opt depigmentation rather than repigmentation.

So, many stories made up which hurt the Michael in a real manner. He took his last breath on 25 June, 2009. But it is true that the
sudden demise of Michael Jackson has generated a wave of awareness in people about vitiligo.


Grafting of Epidermal Sheets for Repigmentation in Vitiligo Dermatologists are trying their best to deal with new ways for the treatment of  Vitiligo. For this purpose, many surgical techniques are experimented such as skin or melanocytes transplantation. Now a day a method is introduced in a research published in J W Dermatology for Vitiligo, “Grafting of Epidermal Sheets for Repigmentation”. It has been also observed that stable lesions cause more repigmentation.
For this, the researchers take 0.1 mm of epidermal sheet splices from buttock with Zimmer air dermatome. To depigment it they protected these grafts to the superficial derma braded skin. Then they grafted 19 people with Vitiligo and 1 with piebalds in this manner. They secured these sheet splices to the host area with silicone web and enclosed them for one week with gauze soaked in salt. After that the grafted areas of patients were exposed to sunlight. The successful results of this research shown that in 4-8 months, 5-100% repigmentation is acquired out of 64% of the grafting sites.
Similarly 18 % of grafting sites achieved 50-70% of repigmentation. So, grafting of epidermal sheets for repigmentation is a new ray of hope for vitiligo patients.

Tacrolimus ointment is a topical Immunosuppressive drug (that is applied to the skin). It is used in the treatment of skin diseases like Eczema and Vitiligo. Tacrolimus was first approved by the Food and Drug Administration (FDA) in 1994 for use in liver transplantation, then it has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, bone marrow, and limb transplants.

A retrospective assessment of 57 children with Vitiligo has been in print in Journal Watch Dermatology February 15, 2005. In this research, children of 4-16 years in age were taken which had all types of Vitiligo (generalized, 58%; segmental, 37%; and acrofacial, 5%) and 43 of them had experienced steroids and phototherapy in the past with inadequate responses. Tacrolimus was applied on these patients for three months.

AS a result, the response rates were better for head and neck than the trunk and extremities (89% vs. 63%). Similarly eyelids had shown better responses. So, this research helped dermatologists to prove that Tacrolimus Ointment is useful for Vitiligo in Children. The response rate also  varied with season. The response rate was 100% in summer and 61% in winter. The spring and autumn were in between with 76% and 81% respectively.


Scientists from Tokyo Medical University and University of Cincinnati had to be experienced by this study of Skin Tone Manipulation. This study has been carried out on Bioengineered Skin Grafts. Bioengineering is the branch of Science which fetched a revolutionary role in all aspects of human life especially in medical (treatment of certain diseases).
It is expected that these bioengineered skin grafts will show the way to vast revolutionizes in the aesthetic results which involve skin grafting such that severe burns, epidermis bullosa, scleroderma, venous leg ulcers, and diabetes. A senior researcher claims that this technique may be helpful in the improvement of pigmentary diseases like Vitiligo and Melasma.
Modern Research shows that mainly Skin Tone Manipulation depends upon Melanin pigment produced by melanocytes which are further  modified by Keratenocytes. Keratenocytes are predominant cells which form outermost layer of human.

Modern Research shows that the conduct of melanocytes can be influenced by the agency of Keratenocytes. This research shows dual benefits. It is not only helpful in the management of pigment disorders but also in the development in the field of cosmetics in new generation in future.



During a research analysis of some traditional herbal remedies for vitiligo Dr. Amala Raman and her PhD student Zhixiu Lin discovered that an extract of a particular plant stimulated the production of melanocytes in cell cultures. After few years the name of that particular extract was revealed to be piperine – the compound that gives black pepper its spicy, pungent flavor. This research was partly funded by vitiligo society.



This research got temporarily suspended due to departure of Dr. Amala to the US and now another team at King’s College London has taken up the challenge. The results of their work would shortly be published in British Journal of Dermatology.



It has been found that synthetic derivatives of piperine can stimulate pigmentation and when its use is combined with UVR it gives frequent and long lasting pigmentation. Furthermore they discovered that four exposures of UVR were sufficient to re-pigment the skin using this combination and the repigmentation results took longer to fade out. They also noticed that piperine properly evened out the skin tone.



The major hurdle that needs to be overcome before piperine is used to treat vitiligo patients is its safety because anything that stimulates melanocytes may conceivably increase the chance of melanoma. It will take many years of further research and development before piperine comes out as a useful and secure vitiligo therapy.



One of the leading causes of skin cancer is sun exposure. Scientists say that
skin cancer can be prevented by avoiding periodic overexposure to sun coz sun’s
UV rays damages DNA in the skin. The main cause of skin cancer is harmful UV
rays but its intensity of risk depends on the skin type and its color.

People who have very fair complexion are more vulnerable to skin cancer than the
people with darker complexion. In most of the cases skin cancer in people with
darker complexion is identified at a later stage.

Vitiligo is often thought to be a precancerous condition but that is not the
case. Due to absence of melanin in people with vitiligo their skin becomes
sensitive to harmful UV rays. Melanin is the pigment which gives us protection
against harmful UV rays but due to absence of melanin in vitiligo patients their
skin becomes susceptible to sun’s UV rays which can result in melanoma.

It has been found that in some cases people with melanoma develop white patches
on skin in the vicinity of their melanoma but these patches are not vitiligo.

Many people think wrinkles and age spots as normal part of aging but these are
caused by excessive exposure to sun. Some of main damages caused excessive
periodic sun exposures are skin cancer, benign tumors, fine & coarse wrinkles,
freckles, mottled pigmentation, sallowness, telangiectasias, and elastosis.

Always use some protection when going under the sun like sunscreens, wear
wide-brimmed hats and protective clothing. Avoid going out in the sun between
10:00 A.M. to 4:00 P.M during the summers.


In my opinion, the short answer to this question is no. Scientists cannot test the efficacy of alternative medicine effectively. This is because modern science works within a strict standard that is at best difficult to apply to a variety of characteristics in alternative medicine.

Modern scientific medicine is based on strict standards that provide scientists with a structure within which testing and experimentation is limited. However, not all phenomenons are necessarily verifiable using this standard and several aspects of alternative medicine are simply outside the modern scientific model.

Let’s start with what should easily be verifiable by modern science. The result of a particular herb should be easily verifiable and should provide reliable results. Problem is, the tests often give different results and do not agree about efficacy of a specific herb. Why? This is where it gets a bit more complex.

In order to examine a specific herb for its medicinal properties and efficacy, the scientists must use the right species of herbs. This is easy to accomplish, however, there are some key differences in the same species, based on how and where it is grown, the time of the day and year it is harvested, the condition of the soil the herb was grown in and the different processing methods. But the modern scientists treat both the herbs as if they were same.

Scientists do not achieve consistent results because they are testing the same species but not the same quality of the herbal extract. Unless the scientists test the same thing there are strong chances of obtaining different results.