This hypo pigmentation disorder includes many disorders with color loss, the most famous is vitiligo.
There are two main reason of generalized reduction in skin pigmentation at birth; it may either occur due to racial origin or due to albinism (is a form of hypo-pigmentary congenital disorder, characterized by a partial or total amelanosis).
In such condition a lack of circulating melanocytes stimulating hormone (MSH) results in Pituitary failure and acquires hypo-melanosis. The localized hypo-pigmentation may also be happened due to a partial or complete loss of melanin (A pigment producing cells).
The main diagnoses of hypo-pigmentary congenital disorder are:
1. Pityriasis Alba.
2. Pityriasis Versicolor.
3. Post inflammatory Hypo-pigmentation.
4. Vitiligo or Lecuderma.
5. Scarring.
6. Lichen sclerosus. ( a long-term problem skin, mostly appear on genital and anal areas)
7. Leprosy.
Pityriasis Alba: It is a common skin condition & is a mild childhood form of eczema; which is usually characterized by dry, fine-scaled & pale patches on the face. This is a self-limiting skin problem, but can be easily treat by the application of any moisturizing creams.
During Pityriasis Alba, we found a lack of active melanocytes in the skin; such condition also makes a decrease in number and size of melanosomes (an organelle containing melanin) in affected area for unknown reasons.
Hypo-pigmented Pityriasis Versicolor: Pityriasis Versicolor is a skin disease which happens due to the Malassezia Furfur (a normal inhibitor of the skin and hair follicles of individuals at puberty and beyond), and results in pale scaly plaques. It is a chronic recurring superficial yeast infestation of the skin; appears when Malassezia got its overgrowth in favorable conditions.
Vitiligo:
A common condition causing loss of skin pigmentation; Vitiligo is a condition which causes white patches to develop on the skin. Any body part can be affected; most of the people with vitiligo do have many white patches in many areas of the body.
Post-inflammatory Hypo-pigmentation: It is a coetaneous disease and is characterized by decreased pigment in the skin, which results in skin inflammation. Post-inflammatory Hypo-pigmentation may be macular, superficial burns or eczema, when it happens as a result of dermal injury with scarring.
Hypo-Pigmentation
